In an alchemical ritual gone wrong, Edward Elric lost his arm and his leg, and his brother Alphonse became nothing but a soul in a suit of armor. Equipped with mechanical "auto-mail" limbs, Edward becomes a state alchemist, seeking the one thing that can restore his and his brother's bodies...the legendary Philosopher's Stone.

In the midst of a heated battle, Ed and Prince Lin of Xing are swallowed whole by the homunculus Gluttony. Will they survive the depths of Gluttony's gullet like Jonah inside the whale, or has Al lost his brother for good? And the political power structure of the military may be irreparably shattered when Colonel Mustang confronts Führer President King Bradley with his horrifying suspicion that Bradley is a homunculous!